Quercetin

Quercetin (95% Flower Extract from Sophora japonica) – 200 mg

 

Styphnolobium japonicum - Wikipedia

What is Quercetin?

Quercetin is a pigment that belongs to a group of plant compounds called flavonoids. Quercetin is found mostly in onions, grapes, berries, cherries, broccoli, and citrus fruits. It is a versatile antioxidant known to possess protective abilities against tissue injury induced by various drug toxicities.

What does it help with in the body? 

Quercetin is a flavonoid, and the previous studies showed that the ingestion of flavonoids reduces the risk of cardiovascular diseases, metabolic disorders, and certain types of cancer. These effects are due to the physiological activity of flavonoids in the reduction of oxidative stress, inhibiting low-density lipoproteins oxidation and platelet aggregation, and acting as vasodilators in blood vessels. Free radicals are constantly generated resulting in extensive damage to tissues leading to various disease conditions such as cancer, Alzheimer’s, renal diseases, cardiac abnormalities, etc., 

People take Quercetin for several reasons, including to boost immunity, fight inflammation, combat allergies, aid exercise performance and help to maintain general health. 

What have the studies shown?

Studies show that quercetin may help reduce inflammation.

In test-tube studies, quercetin reduced markers of inflammation in human cells, including the molecules tumor necrosis factor alpha (TNFα) and interleukin-6 (IL-6).

An 8-week study in 50 women with rheumatoid arthritis observed that participants who took 500 mg of quercetin experienced significantly reduced early morning stiffness, morning pain, and after-activity pain.

They also had reduced markers of inflammation, such as TNFα, compared to those who received a placebo.

The ability of quercetin is claimed to exert many beneficial effects on health, including protection against various diseases such as osteoporosis, lung cancer, and cardiovascular disease. The studies showed that there has been a reduction in the risk of cardiovascular disease in subjects, who had a high intake of flavonoids.

Increasing evidence indicates that quercetin supplementation may be beneficial in its treatment of COPD. In the previous preclinical study, it has been demonstrated a 4-fold increase in plasma quercetin levels significantly decreased lung inflammation and prevented disease progression. 

Quercetin has been reported to have features of neuroprotection in rat brains when used in combination with fish oil. Subsequently, it has also been reported to show beneficial effects against neurodegenerative diseases.

Quercetin supplementation (150 mg/day) reduced systolic blood pressure and plasma oxidized LDL concentrations in overweight subjects in a 5 week double-blind trial. 

What are some contraindications?

Quercetin is found in many fruits and vegetables and is safe to consume. As a supplement, it appears to be generally safe with little to no side effects. When consumed in food, quercetin is safe for pregnant and breastfeeding women.

A study determined that the quercetin safety dose is 945 mg/m2. Some milder symptoms of quercetin include headaches, stomach aches and tingling sensations. In toxic doses, quercetin causes emesis, hypertension, nephrotoxicity, and reduction in serum potassium.

However, studies on the safety of quercetin supplements for pregnant and breastfeeding women are lacking, so you should avoid taking quercetin if you’re pregnant or nursing.

Source:  https://www.healthline.com/nutrition/quercetin

For more information about Quercetin: 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214562/#:~:text=Quercetin%2C%20a%20plant%20pigment%20is,induced%20by%20various%20drug%20toxicities

https://www.healthline.com/nutrition/quercetin

Compare to: Thorne – Quercetin Phytosome ($38)